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Acta cir. bras ; 30(2): 94-99, 02/2015. graf
Artículo en Inglés | LILACS | ID: lil-741029

RESUMEN

PURPOSE: To investigate the effectiveness of low-level laser therapy (LLLT) on gastrocnemius muscle morphology and Myod imunoexpression in a model of dorsal burn in rats. METHODS: Sixteen male Wistar rats were distributed into two groups: control group (CG): rats submitted to scald burn injury without treatment and laser treated group (LG): rats submitted to scald burn injury and treated with laser therapy. Fourteen days post-surgery, gastrocnemius muscle was evaluated being the specimens stained with HE and morphometric data was evaluated. MyoD expression was assessed by immunohistochemistry. RESULTS: The results showed that laser treated animals presented more organized tissue morphology compared to the non-treated animals, with a higher number of nucleus in the fibers. Also, the cross sectional area of the fibers and the MyoD immunoexpression in the laser treated groups was higher. CONCLUSION: Low-level laser therapy had positive effects on gastrocnemius muscle, improving tissue muscle morphology, increasing cross sectional area and MyoD immunoexpression. .


Asunto(s)
Animales , Masculino , Quemaduras/radioterapia , Terapia por Luz de Baja Intensidad/métodos , Músculo Esquelético/efectos de la radiación , Proteína MioD/análisis , Quemaduras/metabolismo , Quemaduras/patología , Recuento de Células , Modelos Animales de Enfermedad , Inmunohistoquímica , Fibras Musculares Esqueléticas/efectos de la radiación , Músculo Esquelético/patología , Proteína MioD/efectos de la radiación , Ratas Wistar , Reproducibilidad de los Resultados , Piel/lesiones , Piel/efectos de la radiación , Factores de Tiempo , Resultado del Tratamiento
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